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How the world got lost on
the road to an anti-aging pill
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April 24, 2021: by Bill Sardi with Matthew Sardi
Resveratrol continues to astound researchers and the public alike. Not only does resveratrol exhibit virucidal properties (virus killing), it works indirectly in the gastric tract to reduce intestinal permeability (leaky gut). It accomplishes this via its anti-inflammatory properties.
Resveratrol is a prebiotic, not a probiotic. Consumers are more familiar with probiotics like acidophilus and Bifidus sold in health shops.
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April 12, 2021: by Bill Sardi
It’s April 7, 2021 and Newsweek magazine posted up a review article about the state of anti-aging pills. Any avid longevity seeker who has been following this story over time would have thought it was written over a decade ago. The promise of an anti-aging pill is getting old.
An anti-aging pill is always another decade away, another long-term controlled human trial, a conclusive meta-analysis providing compelling data to build a consensus of experts. But then again, that will never be enough.
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March 31, 2021: by Bill Sardi
As the world has learned in the past year, when forced to use natural remedies like vitamins C & D and zinc because there were no prescription drugs or vaccines at hand that specifically address a newly mutated coronavirus, the world experienced a massive decline in heart attacks, the inexplicable vanishment of influenza-related deaths (flu deaths were massively overstated anyway and the flu was recategorized as a coronavirus), and other respiratory diseases, cancers and common maladies faded away. And there were no mass side effects reported from consumption of these natural remedies as predicted by health agencies that warn the public away from these nutraceuticals.
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February 11, 2021: by Bill Sardi
The focus of this report is resveratrol and its profound and unparalleled anti-COVID-19 properties. But before this report addresses resveratrol, some background information is needed.
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January 5, 2021: by Bill Sardi
Alcohol consumption is up 500% in America with lockdown and quarantine measures in place. So is anxiety.
The number of mentally depressed people in the world is estimated to be 300 million. Most likely that number has risen considerably with the COVID-19 lockdowns.
The red wine molecule resveratrol is the ideal multifunctional molecule for anxious, depressed or stressed individuals during an epidemic lockdown.
Resveratrol was recently shown to molecularly reverse internal markers of mental depression among laboratory mice that were restrained in their cages. A report published in Neurochemical Research Jan. 3, 2021 stated the effect was profound.
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January 3, 2021: by Bill Sardi
Researchers in Spain now show that a modest dose of the red wine molecule resveratrol (~100 milligrams in humans) reverts aging changes in old animal hearts to more youthful patterns. This research suggests it is never too late to benefit from resveratrol supplementation. These beneficial changes correlated with increased levels of sirtuin1-survival gene protein.
Resveratrol reduced markers of inflammation (tumor necrosis factor or TNF) and interleukin 10. Inflammaging is the descriptive term used to characterize aging changes throughout the human body with advancing age.
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December 30, 2020: by Bill Sardi
There is convincing evidence, both experimental and observational, that fish, chicken and beef from animals that consume resveratrol-fortified diets produce healthier and less-contaminated sources of food.
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December 27, 2020: by Bill Sardi
Food poisoning is all too common. Undercooked poultry is a major cause. While there are ~250 foodborne illnesses, campylobacter jenuni is among the top five largely because poultry is consumed by most of the population.
Symptoms start 2-5 days following ingestion of campylobacter. The Centers for Disease Control estimates 1.5 million people in the U.S. become ill from Campylobacter infection every year. Common symptoms are diarrhea (often bloody), fever, stomach cramps, nausea, vomiting and fever, which usually last a week.
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December 16, 2020: by Bill Sardi
Since 2013 it has been known that red wine molecules restore lost vision to even the oldest patients with macular degeneration. But now science works backwards to figure out why.
Researchers report a combination of molecules found in concentrated form in red wine, without alcohol, work synergistically to inhibit undesirable new blood vessels in a lab dish study. Resveratrol alone was not able to prevent these abnormal blood vessels. The key molecules that produced the synergistic effect were resveratrol and quercetin.
With advancing age blood circulation to the back of the eyes is often reduced. Lacking oxygen, abnormal blood vessels crop out to deliver needed oxygen to the retina, a process called angiogenesis of neovascularization, but in so doing, destroy the visual center of the eyes (the macula).
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December 13, 2020: by Bill Sardi
Longevity researchers recently reviewed 7 studies that compared resveratrol to a calorie restricted diet in mice. They concluded resveratrol only moderately mimics some of the aspects of a lifespan-doubling limited calorie diet and produces inconsistent results in humans.
In 2004 the world heard of the promise of super-longevity achieved via a small molecule found in red wine. Our genes are modifiable, they are not fixed. Humans can even reverse biological versus calendar aging.
In 2006 resveratrol was shown to improve the health and survival of laboratory mice on a high-calorie diet.
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