Comprehensive Library Of Resveratrol News

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  • How to Play the Game of Life and Go Into Extra Innings

    March 28, 2019: by Bill Sardi

    Sweat, Fast, Donate Blood, Limit Red Meat, Supplement With Iron/Copper Chelators (Fisetin, Quercetin, Resveratrol, IP6 Rice Bran, Nucleotides) To Reduce The Population Of Senescent Cells In Your Body & Live Longer & Healthier Than You Ever Imagined

    To Stay Young… Kill “Zombie” Cells — Scientific American

    Now you and your loved ones can play the game of life into extra innings and they aren’t going to have to send in a pinch runner for you, and you won’t be forced to retire and you can still hit home runs!

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  • Longevity Seekers Need To Employ Anti-Senolytic Agents Before Frailty Begins In Their Ninth Decade Of Life.

    March 6, 2019: by Bill Sardi

    Longevity seekers may not have sufficient information to give them an understanding of what lies ahead as they enter their eighth and ninth decades of life. The problem is not cataracts, erosion of bone (osteoporosis), loss of muscle mass, heart failure or mental decline per se, that are inevitable consequences of living long. These are individual features of aging that emanate from a problem called cell senescence.

    During the years of youth cells divide (mitosis), die off (called apoptosis) and renew themselves (daughter cells). But with advancing age a significant portion (5% to 20%) of cells don’t divide and renew.

    Recently it has been discovered that these zombie senescent cells drive aging and increase frailty and mortality. Some 25-50% of people over the age of 85 today are frail. Frailty is 15% in the elderly population and 54% among those hospitalized. When senescent cells were injected into young mice, they become old and frail, and they also died prematurely. This is newly recognized science.

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  • Resveratrol Unblocks Blood Vessels In The Brain, May Rapidly Unlock Lost Memories

    February 13, 2019: by Bill Sardi

    By chance a research group at Cornell University discovered that white blood cells known as neutrophils stick to the smallest blood vessels in the human body (called capillaries) and reduce blood flow to the brain.  Unblocking these capillaries with a monoclonal antibody (antibody blockers) that prevent the adhesion of roaming neutrophils to capillary walls improves blood flow in the brain.  An immediate restoration of mental performance and working memory of laboratory animals was observed.

    The discovery has profound application among adults who face age-related memory decline.  The ground-breaking report was published in the journal Nature Neuroscience.
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  • Longevity Seekers: To Live Longer Skip The Expensive Young Blood Plasma Infusions And Supplement Your Diet With Rice Bran IP6

    January 10, 2019: by Bill Sardi

    Nothing like putting a damper on the plans of billionaire oligarchs who have cooked up an expensive cure for human aging that very few but themselves can afford.  It’s the transfer of blood plasma from a young donor to an old recipient to produce an anti-aging effect.  The idea was fostered by recently published studies that show the conjoining of blood circulation of a young animal with an old one results in the old animal becoming younger biologically.

    That experimental procedure is called parabiosis.  Of course, old humans aren’t stitching their arteries together with younger people as they did in the animal lab but rather receive infusions of blood plasma from young donors. [Nature 2015]

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  • What Does Low-Dose Radiation From An A-Bomb Have To Do With Resveratrol and Longevity?

    January 4, 2019: by Bill Sardi

    The title of unluckiest and unhappiest man in the world was assigned to Mr. Tsutomu Yamaguchi who during WWII was A-bombed at Hiroshima, Japan and then was evacuated to Nagasaki where he survived a second A-bomb attack.  The A-bombs did not shorten his life.  He lived 93 years.  Another survivor, Sunao Tsuboi, at the age of 20 was 1.2 kilometers from the A-bomb epicenter in Hiroshima.  He is alive and healthy today at age 93 (2018).

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  • Resveratrol And A Woman’s Heart

    January 2, 2019: by Bill Sardi

    Main points:

    • Women experience a different form of heart disease than males, largely ischemic (oxygen-deprived) heart disease.  This can lead to heart failure.  This form of heart disease occurs in the post-menopause and is more prevalent with advancing age.  Men generally experience disease of the coronary arteries that supply the heart with oxygenated blood.
    • Many women fear breast cancer more than heart disease even though cardiovascular disease kills 7 times more women every year than does breast cancer.
    • Women experience loss of calcium from bone as estrogen production declines.  That calcium is deposited in arteries, making them less flexible and elastic.  That can lead to a decline in the pumping of oxygenated blood to the heart (diastolic blood pressure) and eventual death of the heart itself.
    • Estrogen therapy is posed as a protective factor but many women are wary of estrogen replacement.  Estrogen produces elevated levels of an intra-arterial gas known as nitric oxide that dilates (widens) arteries.  Resveratrol exhibits the same nitric oxide activation as estrogen.
    • Resveratrol, an estrogen-like molecule (1/7000 the hormonal activity of estrogen) is reported to be as or more effective as a common drug used to treat heart failure and doubles as a preventive for breast cancer.  In the animal lab, female rodents experience a more favorable response from resveratrol than males in regard to heart health.

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  • What It’s Like To Be 107 Years Old?

    December 26, 2018: by Bill Sardi

    Oldest barber: 107 years old

    Photo: Corey Kilgannon

    Before I get to the incredible story of Anthony Mancinelli, age 107, there is also the story of Joao Coelho de Souza, born March 10, 1884 (there isn’t supposed to be anybody alive that was born in the 1800s) who has records to prove he was 131 years old in 2016. Is the Coelho de Souza report valid?

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  • Dear Doctor: Would You Take Resveratrol After Your Own Heart Attack?

    December 13, 2018: by Bill Sardi



    This report pertains to:

    • Bioavailability/ metabolism
    • Dosage
    • Safety
    • Potential side effects
    • Molecular synergism

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    December 10, 2018: by Bill Sardi

    In the anti-aging pill arena 2018 has been the year of senolytic drugs – the prospect that synthetic molecules could soon erase the ravages of aging produced by a progressive aging process called cell senescence.

    Four major milestones have been achieved in rapid fashion.These four developments started in 2011 with an animal study where the destruction of “senescent” cells improved the lifespan and health span of laboratory mice.That was followed by (2) the identification of small natural molecules that are capable of clearing the body of “senescent” cells; then (3) these molecules were then shown to improve the lifespan and function of aged mice; and (4) pre-clinical studies show these molecules are successful in quelling a wide range of maladies.

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  • Don’t Take It For Granted That You Will Live As Long As Your Grandfather

    November 8, 2018: by Bill Sardi

    Musings (Periods of Reflection or Thought.) About Living An Extra-Long Life

    Some 14 years ago I ventured to Harvard Medical School to interview Harvard Professor David Sinclair, who became the pied piper of anti-aging pills with his published discoveries involving the red wine molecule resveratrol. I ended up writing a book THE ANTI-AGING PILL (now a rare book at Amazon) and was confronted by an unexpected fact: most people don’t want to achieve super-longevity. They would rather retain a youthful appearance over living long enough to drool at the mouth, need to wear diapers to handle their incontinence and be drugged into mindlessness. This is what modern medicine has made of old, old age. As someone once said to me: “What people want is thick hair, smooth skin and Viagra baby!” I ended up re-titling my book to THE RED WINE PILL, which was more appealing.

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