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January 3, 2021: by Bill Sardi
Researchers in Spain now show that a modest dose of the red wine molecule resveratrol (~100 milligrams in humans) reverts aging changes in old animal hearts to more youthful patterns. This research suggests it is never too late to benefit from resveratrol supplementation. These beneficial changes correlated with increased levels of sirtuin1-survival gene protein.
Resveratrol reduced markers of inflammation (tumor necrosis factor or TNF) and interleukin 10. Inflammaging is the descriptive term used to characterize aging changes throughout the human body with advancing age.
Remarkably, these restorative changes were evident in old laboratory animals and suggest reversal of aging.
Researchers said: “We observed that when old animals were supplemented with resveratrol, the expression of genes related to those processes were reverted to levels observed in young animals. Our results indicate that resveratrol might be an interesting approach not only for preventing age-related increases in inflammation and oxidative damage, but also for reverting those changes once they take place. “
The study was conducted at Complutence University, Madrid, Spain, and published in the European Journal of Nutrition, Jan. 2, 2021.
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