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How the world got lost on
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May 7, 2011: by Bill Sardi
Researchers in Sweden report that a single dose of resveratrol combined with a platinum-based anti-cancer drug prevented resurgence of ovarian cancer in a laboratory dish. This finding is quite extraordinary given that relapse of ovarian cancer following platinum-based drug therapy (cisplatin, carboplatin) is common and 5-year survival for this type of cancer is only 40-45%.
Resveratrol allowed investigators to use low-dose chemotherapy.
A picture of tumor cell growth after 3 days is shown here (below).
The platinum + resveratrol treated tumor cells could not resume growth. Tumor cells treated with platinum drugs alone or resveratrol alone resumed growth.
While resveratrol is known to up-regulate the Sirtuin1 survival gene in some tissues and organs, in this experiment Sirtuin1 was not up-regulated by resveratrol.
Researchers concluded that “Clinical co-treatment with resveratrol may therefore have remarkable potential.” Results of the experiment were published in a recent issue of Cancer Chemotherapy & Pharmacology. – © 2011 Bill Sardi, ResveratrolNews.com Not for posting on other websites.