Introducing: the first comparison (we know about) of competing resveratrol supplements. Unfortunately it does not cover all products on the market as new offering come on the market ALMOST MONTHLY.

On our front page is our Editorial "Buyer Beware" about the almost-total lack of truth in labeling by so many producers in the supplements industry. Whether it's Vitamin D or Resveratrol, what you see on the label may NOT be what you are swallowing. (It may be more, it may be less, it may, in the case of much resveratrol, be biologically dead) So we welcome the press release below by Longevinex who submitted their resveratrol product, plus that of five competing resveratrol products, to an independent and well-regarded lab for analysis. And have published the results:

Longevinex ® (Licaps ®, Capsugel®) Preserves Trans Resveratrol in Red Wine Pills Six Times Better Than Conventionally-Made Pills

Independent laboratory studies of Longevinex® resveratrol/red wine extract dietary supplements, encapsulated in an airtight gelatin capsule (Licaps®, Capsugel®), confirms that this method of encapsulation inhibits undesirable degradation and molecular conversion of resveratrol over an extended period of time. Longevinex® (Licaps®) capsules retained total resveratrols 40% better, and minimized undesirable molecular conversion of trans resveratrol to cis resveratrol more than 6.5 times better, than conventional tablets or capsules.

ê Scroll to bottom for Important table at the base of this screen

San Dimas, CA (PRWEB) March 13, 2006 -- Independent laboratory studies of Longevinex resveratrol/red wine extract dietary supplements, encapsulated in an airtight gelatin capsule (Licaps, Capsugel), confirms that this method of encapsulation inhibits undesirable degradation and molecular conversion of resveratrol over an extended period of time. Longevinex (Licaps) capsules retained total resveratrols 40% better, and minimized undesirable molecular conversion of trans resveratrol to cis resveratrol more than 6.5 times better, than conventional tablets or capsules.
 
Resveratrol, a molecule found in red wine and other botanical sources, is widely known to be the chief molecule that produces the “French Paradox,” the fact that the French live longer and healthier despite a high-calorie, high-fat diet.* Researchers are aware that resveratrol, can degrade, and that trans resveratrol, the primary active form, can convert to the less active cis resveratrol, upon exposure to light, heat and oxygen during encapsulation and storage.

Longevinex, a proprietary combination of red wine and other antioxidant stabilizing molecules obtained from botanical sources, is the only red wine resveratrol dietary supplement to mimic research-grade production standards, and is never exposed to light, oxygen or heat during production or storage. Studies conducted by an independent laboratory shows Longevinex (Licaps) retains 96% (87-100%) of total resveratrols over a 2-year period.

For comparison, 5 brands of conventionally-made resveratrol pills (2-piece gelatin capsules or tablets) averaged a 44% (12-90%) loss of total labeled resveratrols over time.

Three different production lots of Longevinex capsules maintained high amounts of trans resveratrols (93-98% of labeled dosage) over a 2-year shelf life period (+- 4-5% for variance in raw materials). On average, there was only 4% undesirable conversion to cis resveratrol in Longevinex capsules versus 26% in 5 competing brands of resveratrol supplements. Trans resveratrol, considered the more biologically active molecule, is the form of resveratrol known to activate the Sirtuin 1 DNA-repair gene.

Resveratrol has received recent attention in news and scientific reports for extending the life of fish [Current Biology, Feb. 7, 2006 and as a biological mimic of calorie restriction.* [Scientific American, March 2006

Another recent report suggests resveratrol fulfills the definition of a preconditioning compound that promotes a healthy heart.* [Molecular Interventions, Feb. 2006

Biologists have also recently documented that trans resveratrol activates a DNA repair gene (Sirtuin 1) that is associated with the prolonged lifespan of yeast cells, fruit flies, roundworms, and most recently, fish.* [Nature, August 5, 2004

Longevinex introduced its synergistic combination red wine extract dietary supplement (trans resveratrol, quercetin, rice bran, lecithin) in 2004 (patent applied for), which is designed to synergistically preserve and prolong the biological action of trans resveratrol in a dietary supplement. Unlike wine, Longevinex contains no alcohol, sugar or sulfite preservatives. For more information, visit www.longevinex.com 

*This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

SEE TABLE BELOW FOR LAB REPORT

 

                      

Stability & Shelf Life of LICAPS
Longevinex® Red Wine extract Capsules
(Patent Applied for)

Brands Resveratrol
Dietary Supplements
Labeled
Dosage
Per Pill
Total
Resveratrol
Milligrams
Percent of
Labeled
Resveratrol
Trans
Resveratrol
Milligrams
Cis
Resveratrol
Milligrams
Ratio of
Trans-resveratrol to
Cis-resveratrol
Longevinex Lot A
Licaps Sealed Capsule
40 mg39.5699%38.780.78298/02
Longevinex Lot B
Licaps Sealed Capsule
40 mg34.8587%32.272.58093/07
Longevinex Lot
Licaps Sealed Capsule
40 mg41.53100&39.751.77596/04
Longevinex Average40 mg---96%------96% trans
4% cis
Product A
Clear Gelatin Capsule
20 mg14.3672%12.711.65688/12
Product B
Clear Gelatin Capsule
75 mg38.8952%35.543.35191/9
Product C
Clear Gelatin Capsule
15 mg11.8779%4.8766.99741/59
Product D
Tablet
16 mg14.0688%5.9518.10942/58
Product E
Tablet
20 mg2.00210%1.0210.98151/49
Total Avg. Other Brands-------56%------74% trans-resveratrol
26% cis-resveratrol
 
 

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