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How the world got lost on
the road to an anti-aging pill
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February 23, 2015: by Bill Sardi
A decade after the red wine molecule resveratrol (rez-vair-ah-trol) was introduced as an anti-aging pill, molecular biologists, as they are called, have introduced a whole new strategy that promises to produce nearly ageless humans who will live an indefinitely long and healthy lifespan.
These new “high-brow” youth pills come sans all the hype and hyperbole that accompanied resveratrol dietary supplements when they were first introduced and marketed by online hucksters who offered a free bottle of red wine pills to consumers who suddenly found their credit cards being billed each month without their knowledge.
February 19, 2015: by Bill Sardi
After a decade of scientific misdirection the discoveries involving the red wine molecule resveratrol unrelentingly continue to be published in scientific journals. Human studies are beginning to show resveratrol is relatively safe (safer than aspirin) and remarkably effective in human studies involving maladies of the eyes, brain, liver and heart, particularly when taken in modest but higher-than-dietary-level doses. Its versatility to address so many biological factors that affect aging is nothing less than remarkable. Among these reported advances is an astonishing discovery involving the aging human brain.
Small hemorrhages in the brain are now believed to be the cause of age-related mental decline, not the widely reported beta amyloid brain plaque or excessive acetycholinesterase enzyme that literally erases the brain chemical acetycholine, known as a memory molecule. [Nature Reviews Neurology May 2006; MedScape June 17, 2011] Acetycholinesterase inhibitors (Aricept, Exelon, Cognex, Razadyne) have been a flop for Alzheimer’s disease memory loss. [European Journal Clinical Pharmacology July 2005]
February 15, 2015: by Bill Sardi
In the wake of the Attorney General of the State of New York maligning herbal supplements, to claim herbal remedies sold in major store chains are mislabeled and often contain nothing more than powdered rice and houseplants as fillers, an MIT-based nutraceutical (aka dietary supplement) company has been spawned to introduce a scientifically valid anti-aging pill.
Dietary supplements, widely dismissed by physicians for not being “FDA approved” and unfairly maligned by the research community and the news media, may finally be getting some respect. But only in the context that an anti-aging pill is beyond the charter of the FDA which is to approve molecules, both natural and synthetic, that are safe and effective in the prevention, treatment or cure of disease. Aging is not considered a disease per se and conclusive evidence an anti-aging agent works might take decades to validate. So the more economical, more practical route of introducing an anti-aging pill as a dietary supplement has been taken by one of the most esteemed scientific centers in the world – Massachusetts Institute of Technology.
February 9, 2015: by Bill Sardi
February 2, 2015: by Bill Sardi
Delivered at the Sixtieth Annual Awards Dinner, National Health Federation
Woodland Hills, California, January 31, 2015
Public speaking coaches suggest you size up your audience before you deliver a speech. I’m told there are three ways to segment an audience; those who already embrace what I have to say; those who stand in the middle and need further convincing and those who oppose or disagree with what I have to say. I’m told those who oppose or disagree will not move all the way to embracing my thoughts, that the best I can expect is for them to move towards the middle and those in the middle move towards what I am going to suggest here tonight.
January 29, 2015: by Bill Sardi
About 1 in 5 people are walking around with a gene variant that confers them with extra brain power in the area of decision making, planning, working memory and problem solving. That is the remarkable discovery being reported today and there may be a way for others who don’t carry this variant gene to get the same superior brain power effect by supplementing their diet with vitamin D and the red wine molecule resveratrol.
January 28, 2015: by Bill Sardi
January 27, 2015: by Bill Sardi
You’ll have to save your own life from sudden-death heart attacks; cholesterol-lowering drugs don’t work for this most common type of heart seizure.
If you are rushed for time and don’t have a few minutes to spend reading the entire text of this short report, in a nutshell, if you are a full-grown adult over age 30 and you have a family history of heart disease, and you are a smoker [Journal American College Cardiology 1985], or you drink too much alcohol [American Heart Journal 1992], and you carry a lot of belly fat [Heart Feb 1, 2015], you should supplement your diet with magnesium and omega-3 fish oil and take red wine pills (sans alcohol) in order to avert a drop-dead heart attack.
December 29, 2014: by Bill Sardi
2014 was another year of great promise and inexcusable dawdling by the research community as well as intentional disparagement of what may be the most profound health and longevity molecule ever discovered — resveratrol. Strikingly, there are no human clinical trials for resveratrol for heart disease or cancer, two of its most promising applications. For now, lab rats will be the primary beneficiaries of this remarkable molecule.
One thing is for sure, the research community isn’t taking its foot off the pedal – just over one thousand published studies, commentaries and reviews about resveratrol were posted at the National Library of Medicine this year. That is out of a pool of 7000 published reports dating back to 1978. [PubMed.gov Accessed 12/18/2014]
December 26, 2014: by Bill Sardi
Well, we are getting the message loud and clear. Any anti-aging pill is going to be an expensive and controlled prescription drug rather than a widely available and economical nutraceutical whether consumers like it or not. The masses of the world won’t likely be able to afford it and doctors will extract their cut along with Big Pharma or the world will be left to wallow in the curse of aging.
While the red wine molecule resveratrol has been proposed as an anti-aging pill over the past decade, an FDA-approved drug – rapamycin (ask) Sirolimus) — just danced past it by taking its first successful baby-step as an anti-aging drug. There are no human trials that measure a marker of aging and resveratrol.