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How the world got lost on
the road to an anti-aging pill
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May 17, 2010: by Bill Sardi
A month doesn’t go by these days that some researchers don’t discover another genetic pathway that promotes longevity. This time it’s about the PTEN gene, said to be a tumor suppressor gene. The more active the PTEN gene, and the less active the ARRESTIN gene, the longer roundworms lived. Roundworms without their ARRESTIN gene live about 30% longer. This research is published in the May 14 issue of the Journal of Biological Chemistry.
While investigators claim their research may lead to molecules that inhibit ARRESTIN and activate PTEN, such molecules have already been identified – namely molecules commonly found in red wine and soybeans — resveratrol, quercetin and genistein.
Resveratrol continues to astound. Resveratrol has many gene targets where it has been demonstrated to exert broad biological activity as an anti-inflammatory, anti-clotting, anti-cholesterol, anti-depressant, anti-viral, anti-fungal, anti-bacterial, anti-brain plaque (beta amyloid), anti-obesity agent. These properties must be safely demonstrated in humans with doses that are proven to be safe. – ©2010 Bill Sardi, exclusively for Reserveratrolnews.com