test your knowledge
How the world got lost on
the road to an anti-aging pill
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September 26, 2011: by Bill Sardi
While online scientific reports published in the last 30 days, registered at Pubmed.gov– the National Library of Medicine’s access page to thousands of scientific journals, were saying the red wine molecule resveratrol (rez-vair-ah-troll) protects heart muscle cells prior to a heart attack, blocks lesions that occur in the back of the eyes in an animal model of diabetes, has the potential to ward off age-related brain disorders and has strong anti-tumor activity, a number of major news media outlets were airing headlines stories which said something to the contrary:
Red wine no fountain of youth after all? What new study says – CBS News
What’s In That Wine Glass May Not Prevent Aging After All – National Public Radio
Scientists Question Resveratrol Longevity Products – Red Orbit
How could major news sources get the story about resveratrol so wrong?
The studies that news reports referred to, published in Nature magazine, had nothing to do with resveratrol.
Researchers had a little mud on their face when they reported a gene target (Sirtuin1) for calorie-restricted diets may not be a valid target after all. When the Sirtuin1 gene was removed from roundworms prior to being placed on a limited calorie diet, a known way of doubling the lifespan of most life forms tested, the roundworms lived longer. Sirtuin1 had no effect. It was a stunning blow for anti-aging researchers who were developing drugs with Sirtuin1 as their primary gene target.
So how these major news sources twisted the story to say that red wine resveratrol pills are of worthless value is bewildering.
True, resveratrol is a Sirtuin1 gene-targeting molecule, but that is not all it does. In fact, it targets many hundreds of genes in a superior manner to any man-made drugs.
This reporter requested these mistaken news stories be withdrawn. It’s such an oddity that major news sources would make such a big error in reporting. Was there some agenda here, to get the public to prematurely dismiss resveratrol pills as having any future prospect of conquering aging?
Nor does it make any sense that a major pharmaceutical company has abandoned further research and development of a resveratrol-based drug when this molecule continues to astound researchers worldwide.
Basic research involving resveratrol is being reported in volumes. Researchers are pursuing a number of applications for this red wine molecule in combination with existing therapeutic drugs and as a stand-alone medicine, yet it biggest calling, in coronary heart disease, has yet to attract even one research center to put it to a test in a human trial 8 years after it was identified as the key molecule in The French Paradox. The red wine-drinking French have the highest number of centenarians per capita among all developed nations and have a very low rate of heart disease despite a diet rich in fats and calories.
No researchers were advising consumers to throw away their resveratrol pills which have already been shown to do what no drug can do – protect the heart against a heart attack before it occurs. While this has only been demonstrated in the animal lab, there is no ethical way to demonstrate it in humans. Researchers subject animals to intentionally-induced heart attacks to show that resveratrol provokes the synthesis of three protective chemicals prior to a heart attack that turn an otherwise sudden-death heart attack into a non-mortal event.
Even more strange, when the primary researcher who made this discovery, Dipak Das at the University of Connecticut, published his studies, which were later duplicated and confirmed by researchers at the National Institutes of Health, not a single news source in America chose to report on it. Hey, it’s not as if this is a cure for lumbago or pimples. This is a life-and-death matter and the news media has completely missed it.
Are we so brainwashed over cholesterol-lowering statin drugs that have no need to look any further? According to John Abramson of Harvard Medical School and author of Overdosed America, there is simply no evidence that cholesterol reduction reduces the risk of dying from coronary artery disease for healthy individuals, many whom take statin drugs. But hey, we don’t want any journalists to lose their jobs reporting the billions of dollars of cholesterol-lowering drugs are of useless value for healthy individuals.
Furthermore, aspirin is failing to prevent heart attacks due to aspirin resistance and improper dosing (81-milligram baby aspirin tablets are ineffective). Resveratrol thins the blood like aspirin does and widens blood vessels in the heart to maintain circulation, something aspirin does not do.
Having crafted a resveratrol pill, spent $20,000 to get research studies done, $40,000 to produce an online film of this discovery and $23,000 to have this news of discovery delivered to the doorstep of the nation’s news media, only to have it ignored while hundreds of thousands of American die annually due to sudden-mortal heart attacks, suggests what? Population control, protection of the pharmaceutical industry, what?
The public also appears to be brain dead on this life-and-death issue. Who is the public waiting for to give them permission to take a resveratrol pill? – © 2011 Bill Sardi, ResveratrolNews.com