Comprehensive Library Of Resveratrol News

Biotechnologist Dr. Bruce Bryan emails to say his grandmother, who lived to 109 years of age, in good health most of the way, because he gave her 5 milligrams of deprenyl every morning.

Deprenyl (selegiline) is a drug that was developed in the 1960s for its anti-depressant effects (it is a monoamine oxidase MAO enzyme inhibitor) and is now primarily prescribed for Parkinson’s disease sufferers (trade names Eldepryl, Emsam, Zelapar, Azilect). It is surprising to learn that deprenyl (selegiline) is a molecule similar to methamphetamine, an illicit street drug, but is not psycho-active nor does it create addiction.

In the mid-1990s animal experiments revealed deprenyl prolongs life, first demonstrated in rodents and then dogs. It also was discovered that Deprenyl not only inhibited MAO but it worked in the brain by increasing the activity of internal (endogenous) antioxidant enzymes catalase and superoxide dismutase (SOD). However, deprenyl doesn’t activate glutathione like resveratrol does.

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