Comprehensive Library Of Resveratrol News

First Report Of Internally-Derived Stem-Cell Survival To Regenerate Damaged Cells In The Human Retina Using Molecular Medicine

North Chicago, IL (December 31, 2012) – The first report using molecular medicine to regenerate damaged tissues in the back of the human eye via use of small antioxidant molecules to promote survival of internally-produced stem cells is being reported today. It may be the first successful report of cellular or tissue regeneration via internally-derived stem cells in all of medicine.

In a newly published scientific book (Advancing Medicine With Food & Nutrients, 2^nd edition, CRC Press (Ingrid Kohlstadt, editor), Dec 2012), Dr. Stuart Richer, OD, PhD, Director, Ocular Preventive Medicine- Eye Clinic at the James A Lovell Federal (Veterans) Health Care Center in North Chicago, presents striking photographic evidence of stem cell regeneration of damaged tissues at the back of the eye of a patient with dry macular degeneration accompanied by restoration of vision after using a nutriceutical comprised of small natural antioxidant molecules.

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For the uninitiated: resveratrol (rez-vair-ah-trol) is known as a red wine molecule that is that is believed to be chiefly, but not solely, responsible for the heart-healthy effects of red wine.

The year 2012 started out with maybe half of all resveratrol pill users abandoning their use after hearing allegations that the leading researcher in the field had committed scientific fraud. The researcher, Dipak Das PhD, working at the University of Connecticut (U CONN), was alleged to have fabricated data to gain research grant money and according to radio talk show host Rush Limbaugh, Dr. Das “made it all up” (the science that is).

While over 350 news sources covered the story, they were simply parroting allegations made by a 5-man U CONN review board, a board that concedes it never read the university’s 60,000 page evidence report and could not produce for Dr. Das’ legal counsel the original evidence disc which it said was lost. In fact, U CONN never gave Dr. Das due process and took its website offline when it was challenged to validate various facts that were egregiously inaccurate. But the damage had been done.

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http://www.reuters.com/article/2012/12/20/us-ageing-hongkong-idUSBRE8BJ0B820121220

By Tan Ee Lyn
HONG KONG | Thu Dec 20, 2012 7:55am EST

(Reuters) – Scientists in Hong Kong appear to have mapped out a formula that can delay the aging process in mice, a discovery they hope to replicate in people.

Their finding, published in the December issue of Cell Metabolism, builds on their work in 2005 which shed light on premature aging, or progeria, a rare genetic disease that affects one in four million babies.

Progeria is obvious in the appearance of a child before it is a year old. Although their mental faculties are normal, they stop growing, lose body fat and suffer from wrinkled skin and hair loss. Like old people, they suffer stiff joints and a buildup of plaque in arteries which can lead to heart disease and stroke. Most die before they are 20 years old.

In that research, the team at the University of Hong Kong found that a mutation in the Lamin A protein, which lines the nucleus in human cells, disrupted the repair process in cells, thus resulting in accelerated aging.

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Researchers have just begun to address the idea of developing multiple-gene targeted drugs for multiple-gene targeted diseases.  Single-gene targeted drugs, like Herceptin, Iressa and Erbitux have been met with disappointment.  A discussion regarding the development of such drugs is published in a recently published edition of Expert Opinion in Drug Discovery.

The ability of these drugs to avoid polypharmacy (when too many forms of medication are used by a patient) is a desired secondary objective.

But in saying that, multiple-gene targeted drugs are also anathema to pharmaceutical companies that have been financially built on the false premise of one drug for each disease.

While these researchers suggest modern pharmacology switch direction and develop multi-gene targeted drugs, for now, modern medicine is dragging its feet over this idea.

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Stem-Cell Technology Fascinates, Resveratrol Therapy Is Ignored.  What Goes Here?

Stem cell technology continues to fascinate researchers and technology-driven males.  Anything that is even alleged to facilitate stem cells becomes wildly popular overnight.  Stem cells, if you recall, are those native unspecialized cells that can turn into heart, brain, muscle and nerve cells.  Stem cells are required for tissue repair.  They have great application for renewal of brain, eye and heart cells that have a very slow cell turnover rate (replace themselves only every few years!).  Once damaged, these are the most difficult tissues to repair.

Matt Ridley, Wall Street Journal writer, says from the top of his recent article on this subject that “the chief medical ambition of those who study stem cells has always been that the cells would be used to repair and regenerate damaged tissue.”  Well, yes, but the added requirement that any developed stem cell technology would reap a huge profit for its inventors.  Of course, that might run in the wrong direction of healthcare reform, which is to find new ways to treat patients at less cost.

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