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How the world got lost on
the road to an anti-aging pill
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October 8, 2011: by Bill Sardi
The anti-diabetic drug Avandia (chemical name – rosiglitazone) is widely associated with increased risk for heart attacks and has been broadly criticized as potentially unsafe. However, the underlying mechanism behind potentially life-threatening events has remained obscure. Furthermore, some studies show this drug induces heart attacks while others do not.
Researchers in The Netherlands took smooth muscle cells (human source) from the lining of blood vessels, grew them in a lab dish, and found that the drug anti-diabetic drug rosiglitazone (Avandia-brand name) accelerates calcification in these cells, a mechanism that could help explain why Avandia is associated with adverse outcomes. 21816156
That Avandia use also leads to accelerated calcium loss from bone suggests another link to side effects caused by Avandia. It appears Avandia doesn’t initiate arterial calcifications but accelerates calcifications via decreased production of a key enzyme (alkaline phosphatase).
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October 2, 2011: by ResveratrolNews
So many times this author has lamented at how brainwashed Americans have become. Shown a picture of a 100-year old man blowing out the candles on his birthday cake, almost every person responds by saying “I never want to live that long.”
Strange isn’t it, the promise of super longevity, what Spanish explorer Juan Ponce de Leon long sought after, to conquer aging, the scourge of humanity, is no longer on the minds of most Americans.
An anti-aging pill didn’t top the list of desired inventions in an MIT survey conducted years ago – beat out by biodegradable plastic, a driverless car and an fully automated home, of all things.
While we may distance ourselves from any idea of lining up to die like people did in the movie Soylent Green, where people who had expired were processed into food in an overpopulated world where food shortages were rampant. But most Americans say they favor quality over quantity of life, as if these two never coexist.
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